Results 61 to 70 of about 10,253,495 (364)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The Social and Communicational Profile of Children Identified with Autism in Ethiopia

Children
Background: In Ethiopia, children identified with autism spectrum disorder (ASD) and their families face substantial challenges in obtaining timely diagnosis and appropriate services, including limited public awareness, cultural stigma, and shortages of ...
Waganesh A. Zeleke, Elleni Damtew Asfaw, Angela Lee, Alanna King, Suzzane Long   +4 more
doaj   +1 more source

Explaining burnout and the intention to leave the profession among health professionals – a cross-sectional study in a hospital setting in Switzerland

BMC Health Services Research, 2018
BackgroundBurnout and the intention to leave the profession are frequently studied outcomes in healthcare settings that have not been investigated together and across different health professions before.
O. Hämmig
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Understanding the atmospheric circulations that lead to high particulate matter concentrations on the west coast of Namibia

Clean Air Journal, 2017
Atmospheric circulations play a significant role in determining the extent and impact of local and regional air pollution. The Erongo Region, located in the western part of Namibia, falls within the west coast arid zone of southern Africa, and is ...
H Liebenberg-Enslin, H Rauntenbach, R von Gruenewaldt, L Burger   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Health outcomes in hospitalised and non-hospitalised individuals after COVID-19, an observational, cross-sectional study

Communications Medicine
Background Both hospitalised (H) and non-hospitalised (NH) individuals may have different symptoms and impairments after COVID-19. We aimed to explore symptoms, mental and physical health after initial COVID-19 for both groups of individuals and the ...
Malin Nygren-Bonnier, Anna Svensson-Raskh, Linda Holmström, Anna Törnberg, Annie Svensson, Daniel Loewenstein, Malin Regardt, Mikael Björnson, Carl Hallberg, Mike Kemani, Anita Mc Allister, Joakim Körner Gustafsson, Alexandra Halvarsson, Urban Ekman, Linda Nordstrand, Susanne Guidetti, Lena Anmyr, Maria Bragesjö, Jenny Åström Reitan, Farzaneh Badinlou, Oili Dahl, Eva Åkerman, Pär Villner, Petter Brodin, Kenneth Caidahl, Marcus Ståhlberg, Artur Fedorowski, Magnus Sköld, Michael Runold, Judith Bruchfeld, Elisabeth Rydwik   +30 more
doaj   +1 more source

Impacts of working environment and benefits packages on the health professionals’ job satisfaction in selected public health facilities in eastern Ethiopia: using principal component analysis

BMC Health Services Research, 2019
BackgroundWorld Health Organization (WHO) predicted that there will be a shortfall of skilled healthcare by 2035 with the greatest shortfall in Africa and Southeast Asia due to satisfaction with payment and incentives.
Hailu Merga, T. Fufa
semanticscholar   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Health Implications of Climate Change: a Review of the Literature About the Perception of the Public and Health Professionals

Current Environmental Health Reports, 2018
Through a systematic search of English language peer-reviewed studies, we assess how health professionals and the public, worldwide, perceive the health implications of climate change. Among health professionals, perception that climate change is harming
J. Hathaway, E. Maibach
semanticscholar   +1 more source