Results 161 to 170 of about 12,945,820 (301)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Self-as-doer and health promotion for patients with chronic disease. [PDF]

J Educ Health Promot
Pishjoo A, Tedadi Y, Tol A, Sadeghi R, Brouwer AM.   +4 more
europepmc   +1 more source

Health promotion and crime prevention : recognising broader synergies

Conclusion: There are a range of synergies, parallels and shared interests that crime prevention and health promotion share. These fields could develop more supportive networks with each other.
Sarre, Rick, Young, Janette
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Editorial: Life skills in school health promotion: challenges and solutions. [PDF]

Front Public Health
Carvalho GS, Vilaça T, Magalhães-Júnior CAO, Darlington-Bernard A.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Oral health promotion in adults with type 2 diabetes-a scoping review. [PDF]

Front Med (Lausanne)
Alholimie Y, Almutairi D, Almarzooq EN, Alabdullah J, Al-Batayneh OB.   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Uvodnik: mednarodni dan medicinskih sester 1998. partnerstvo za zdravo skupnost

Obzornik zdravstvene nege, 1998
Health Promotion, Ottawa Charter, SZO/WHO; priredba/adaptation: Vera Grbec   +2 more
doaj  

Diversifying health promotion

, 2014
The chapter, "Diversifying health promotion" was written by the listed authors including Colleen Reid (Douglas College Faculty). In this innovative collection, leading thinkers in clinical medicine, sociology, epidemiology, kinesiology, education, and ...

core