Results 171 to 180 of about 810,344 (312)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

AI-Enabled Digital Health Promotion and Prevention: Computational Literature Review. [PDF]

JMIR AI
Girão Carrilho M, Costa Pinto D, Wagner R, Rohden SF, Telo de Arriaga M, Quelhas Pinto L.   +5 more
europepmc   +1 more source

Other title: Behavioral Risk Factor Surveillance System

, 2001
application/pdfExecutive Summary Introduction Methodology-- Limitations Interpretation of Results Health Status Health Care Coverage Overweight Cigarette Use Screening for Breast Cancer Screening for Cervical Cancer Diabetes Mellitus HIV/AIDS-- Quality ...
Kansas. Bureau of Health Promotion.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Beyond awareness: mental health promotion requires epistemic diversity, not pathologization. [PDF]

Front Psychiatry
Pisl V, Starcevic V, Horacek J, Vevera J, Beeker T.   +4 more
europepmc   +1 more source

Healthy aging in complex environments : exploring the benefits of systems thinking for health promotion practice

, 2011
Background Many different stakeholders and contextual factors influence the success or failure of health promotion activities. Conventional approaches and evaluation designs underlying health promotion interventions, often explicitly take contextual ...
Naaldenberg, J.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Mapping programmes for mental health promotion in Singapore: A scoping review. [PDF]

PLoS One
AshaRani PV, Ong XE, Karuvetil Z, Chen CSM, Ther L, Cheng L, Subramaniam M, Liu T.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Machine learning in mental health promotion for older adults: a scoping review. [PDF]

BMC Geriatr
Ruan Y, Liang H, Yamamoto S, Lin S.
europepmc   +1 more source