Results 231 to 240 of about 2,131,145 (306)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The role of allied health professionals in health promotion [PDF]

Benson, J., Hilari, K., Lawrenson, J., Needle, J. J., NHS, Petchey, R. P., Scriven, A.   +6 more
core  

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Strengthening the Capacity for Health Promotion: Reflections on Forty Years Since the Ottawa Charter. [PDF]

Int J Public Health
Biehl V, Potvin L, Plunger P, Wahl A, Van den Broucke S.   +4 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

The PRO-GRESS model: A conceptual framework for gender-responsive reproductive health promotion among survivors of child marriage. [PDF]

Dialogues Health
Mulyaningsih EA, Nurhaeni IDA, Anantanyu S, Lestari A, Saptaningtyas H.   +4 more
europepmc   +1 more source

Storytelling for Health Promotion: A Scoping Review. [PDF]

Am J Health Promot
Nagarkar A, Martin G, Sadaniantz K, Iyengar S, Wisniewski HC, Denu MK, Chiriboga G, Forrester SN, Allison JJ, Kovell LC.   +9 more
europepmc   +1 more source