Results 241 to 250 of about 12,945,820 (301)

Sustainability of implementation of health-promotion practice in primary healthcare: a non-randomized parallel group study. [PDF]

BMC Health Serv Res
Nilsagård Y, Nilsing-Strid E.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Octacosanol: A Natural Bioactive Ingredient for Atherosclerosis Prevention and Cardiovascular Health Promotion. [PDF]

Molecules
Yang X, Han H, He Z, Jia M.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

School-based mental health promotion and behavioral modification in pubertal adolescents: A controlled intervention study. [PDF]

J Educ Health Promot
Chongder M, Pahantasingh S, Nayak R, Pradhan J.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Beyond awareness: mental health promotion requires epistemic diversity, not pathologization. [PDF]

Front Psychiatry
Pisl V, Starcevic V, Horacek J, Vevera J, Beeker T.   +4 more
europepmc   +1 more source

Mapping programmes for mental health promotion in Singapore: A scoping review. [PDF]

PLoS One
AshaRani PV, Ong XE, Karuvetil Z, Chen CSM, Ther L, Cheng L, Subramaniam M, Liu T.   +7 more
europepmc   +1 more source

Digital Mental Health Promotion Services for Youth: A Qualitative Study of Help-Seeking Through Mindhelper.dk. [PDF]

JMIR Hum Factors
Kusier AO, Dalsgaard CH, Hoffmann SH, Thygesen LC, Folker AP.   +4 more
europepmc   +1 more source