Results 121 to 130 of about 81,170,443 (266)

Health Research Board annual report 2012. [PDF]

, 2013
The annual report and extracts from the HRB financial statements 2012. Contents: Chief Executive Overview; Health Research - Aligned to national priorities; Delivering on our strategic business plan; Measuring the impact of HRB health ...
Health Research Board (HRB)
core  

Use of Artificial Intelligence in Mental Healthcare, Health Psychology, and Related Research: A Narrative Review to Address Challenges and Opportunities

Health Science Reports
Background and Aims Artificial intelligence (AI) is the process by which a machine learns from a pool of data and can then respond to questions beyond that data set.
Md. Ashrafur Rahman, Evangelos Victoros, Rob Davis, Tariq Duaa, Yeasna Shanjana, Md. Rabiul Islam   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Health Research Board annual report 2023 - part one [English / Irish]

Some key highlights during the year included the HRB making significant contributions to support the work of the Citizen’s Assembly on Drugs Use (CADU).
Health Research Board
core  

Health research in action 2017

, 2017
Actions and outcomes enabled by HRB-funded ...
Health Research Board
core  

Towards Meaningful Consumer and Community Involvement in Health Research: A Qualitative Study of Consumer and Researcher Experiences

Health Expectations
Background Consumer and community involvement (CCI) in health research is recognised as an essential component of ethical, effective and relevant research practice.
Kimberley A. Baxter, Jennifer Muller, David A. Copland, Nadine E. Foster, Emmah Doig, Jessica A. Schults, Karina R. Charles, Adrienne Young, Silvia Manzanero, Tanya Smyth, Lisa Anemaat   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A manifesto for improved lives through health research

In consultation with our members, Health Research Charities Ireland has developed three critical policy asks for your general election manifesto: Ask 1 Over the lifetime of the next Government, increase research and development investment, year-on ...
Health Research Charities Ireland
core  

Health research in action 2019

, 2019
Actions and outcomes enabled by HRB-funded ...
Health Research Board
core