Results 101 to 110 of about 2,322,159 (314)

HEALTH HUMAN RESOURCES PLANNING AND THE DYNAMIC NATURE OF THE HEALTH CARE NEEDS OF POPULATIONS. [PDF]

According to Birch et al., traditional approaches to health human resources planning emphasize the role of demographic change on the needs for health human resources. Marques argues that the new HR within the globally intertwined organization should have
Elvira NICA
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cost of early-stage mycosis fungoides treatments in Spain

ClinicoEconomics and Outcomes Research, 2020
Pablo Luis Ortiz-Romero,1 Octavio Servitje,2 María Teresa Estrach,3 Rosa María Izu-Belloso,4 Ricardo Fernández-de-Misa,5 Fernando Gallardo,6 Noemí López-Martínez,7 Alejandro Pérez-Mitru7 1Dermatology ...
Ortiz-Romero PL, Servitje O, Estrach MT, Izu-Belloso RM, Fernández-de-Misa R, Gallardo F, López-Martínez N, Pérez-Mitru A   +7 more
doaj  

Medizin- und gesundheitsgeschichtliche Paradigmen zur geschlechterspezifischen Ungleichheit seit ca. 1750

Österreichische Zeitschrift für Geschichtswissenschaften, 2011
At first the author reconsiders the leading paradigms of the social history of medicine and health research during the last decades and their different ways to conceptualize gender: medicalization, the medical market place, patients’ history and health ...
Martin Dinges
doaj   +1 more source

Sharing Health Information with Older Adults Through Online Resources in Canada [PDF]

, 2014
Two-page overview of what was learned from a citizen panel on the topic of sharing health information with older adults through online resources in ...
McMaster Health Forum
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Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Healthy from the Start: Co‐Designing Sleep, Nutrition and Physical Activity Resources for Young Shiftworkers—Novel Implementation and Evaluation

Health Expectations
Introduction The increasing prevalence of shiftwork among young adults poses significant health risks, primarily due to its disruptive effects on sleep, nutrition and physical activity.
Alexandra E. Shriane, Sally A. Ferguson, Gabrielle Rigney, Charlotte C. Gupta, Tracy Kolbe‐Alexander, Madeline Sprajcer, Cassie Hilditch, Robert Stanton, Matthew J. W. Thomas, Jessica L. Paterson, Jamie Marino, Grace E. Vincent   +11 more
doaj   +1 more source

HHRU 99:4

, 1999
The Cooperative Health Human Resources Database (CHHRD), developed and maintained by the Health Human Resources Unit (HHRU) since 1973, provides the basis for a number of our regular and special reports.
University of British Columbia. Health Human Resources Unit
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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source