Results 81 to 90 of about 2,322,159 (314)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Inventory update 00 : a regional analysis of health personnel in the province of British Columbia

open access: yes, 2001
The Cooperative Health Human Resources Database (CHHRD), developed and maintained by the Health Human Resources Unit (HHRU) since 1973, provides the basis for a number of our regular and special reports.
University of British Columbia. Health Human Resources Unit
core  

Resources for oral health in Africa

open access: yesFrontiers in Oral Health
Oral health in Africa is often overlooked despite its substantial impact on overall health and well-being. Currently, Africa has a very high prevalence of dental diseases, including untreated dental caries in permanent teeth, severe periodontal disease and oral cancer.
Moréniké Oluwátóyìn Foláyan   +7 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Study on the coupling and coordination relationship between health resource allocation and economic development level in Shanxi province

open access: yesHuli yanjiu
ObjectiveTo analyze the coupling and coordination degree and relative development degree of health resources and economic development in Shanxi province from 2017 to 2021, and to provide reference for promoting the coordinated development of health ...
WANG Xueyang, YAN Yingying, DUAN Zhaoxia
doaj  

A Cost-Aware and Calibrated Explainable AI Framework for Equitable Coronary Artery Disease Risk Stratification Using Minimal Clinical Data [PDF]

open access: yesInfoScience Trends
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. In many clinical settings, particularly those with limited access to advanced diagnostic resources, reliable risk stratification based on routinely available data
Motahhareh Alisoufi   +5 more
doaj   +1 more source

[Human resources for health].

open access: yesRevista peruana de medicina experimental y salud publica, 2011
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openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Integration of health care delivery in the Eastern Mediterranean Region of the World Health Organization

open access: yes, 2000
747-757This paper reviews developments in the integration of health care delivery in the Eastern Mediterranean Region. It describes the integrated intersectoral support of socioeconomic community development [district health systems and basic development
Al Khawashky, M.I.
core  

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