Results 111 to 120 of about 4,976,429 (317)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Other title: Results from Two Thousand Four Kansas Behavioral Risk Factor Surveillance System
"September 2006." "Partial funding for the 2004 Behavioral Risk Factor Survey was provided by cooperative agreement #U58/CCU722793-01 from the Centers for Disease Control and Prevention, Atlanta GA." Includes bibliographical references.Behavioral Risk ...
Kansas. Office of Health Promotion.
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Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung condition distinguished by a complex etiology, poor prognosis and exhibiting high mortality rates.
Qinlin Cui +11 more
doaj +1 more source
Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
"February 1998." "Funding for the 1996 Behavioral Risk Factor Survey was provided by a grant award from the Centers for Disease Control and Prevention, Atlanta, GA." Includes bibliographical references.Acknowledgements Executive Summary Table of ...
Kansas. Bureau for Disease Prevention and Health Promotion.
core
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Implicit and explicit risk perception, affect, and trust : an investigation of food "traffic lights"
Obesity is a health problem in many developed countries and is a growing problem worldwide. In an effort to improve food choices the "traffic lights" nutritional labelling system has been developed.
Burns, Calvin +2 more
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Background Estimating rates of disease importation by travellers is a key activity to assess both the risk to a country from an infectious disease emerging elsewhere in the world and the effectiveness of border measures.
Rachael M. Milwid +7 more
doaj +1 more source

