Results 101 to 110 of about 13,472,376 (354)

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Agradecimento aos revisores

open access: yesABCS Health Sciences, 2020
ABCS Health Sciences
doaj   +1 more source

Protocol for implementing the nested model for AI design and validation in compliance with AI regulations

open access: yesSTAR Protocols
Summary: Here, we present a protocol for implementing the nested model for developing and validating artificial intelligence (AI) systems in compliance with AI regulations.
Akshat Dubey   +3 more
doaj   +1 more source

Intrinsic Health as a Foundation for a Science of Health

open access: yesScience Advances
The health sciences largely focus on disease. However, the interconnected determinants of diseases suggest that we need a Science of Health, a framework to examine the biology of homeodynamics in a changing environment and how this impacts the health we value.
Alan A. Cohen   +11 more
openaire   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Twitter Users with Access to Academic Library Services Request Health Sciences Literature through Social Media

open access: yesEvidence Based Library and Information Practice, 2017
A Review of: Swab, M., & Romme, K. (2016). Scholarly sharing via Twitter: #icanhazpdf requests for health sciences literature. Journal of the Canadian Health Libraries Association, 37(1), 6-11.
Elizabeth Margaret Stovold
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Critique and evaluation of published articles quality of Health Sciences qualitative Researches Journal based on CASP scale

open access: yesJournal of Qualitative Research in Health Sciences, 2020
Introduction: Recently, rate of journals and published article in the medical sciences has grown, but the quality of these journals and published articles should be criticized.
Shokooh Varai   +3 more
doaj  

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Home - About - Disclaimer - Privacy