Results 131 to 140 of about 7,174,113 (351)
Protocol for geographical mapping of pesticide contamination
STAR ProtocolsSummary: Pesticide residues in the environment threaten agricultural and human health. Here, we present a framework for mapping and comparing the contamination levels of pesticides across specific environmental compartments in various regions.
Yabi Huang, Zijian Li
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Introducing a New Hypothesis in the Genesis of Breast Cancer: An Integrative Review
Breast Cancer: Targets and TherapyJan Pawel Andrade Pachnicki,1– 4,* Clara Marie Cayet,1,* Diego Akyo Hoshina dos Santos,1,* Giovanna Braz Junkes,1,* Julia Petry,1,* Maria Eduarda Mendes Hibarino,1,* Vitória Luisa Lodi Carvalho1,&ast ...
Andrade Pachnicki JP +6 more
doaj
Protocol for making forecasts exogenous in the International Futures model
STAR ProtocolsSummary: Understanding future dynamics and trends in human and natural development is foundational for creating appropriate policy strategies to address planetary and development challenges. Here, we present a protocol for adding exogenous series for key
José Solórzano +8 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Clinical applications of nanoprobes of high-resolution in vivo imaging
iScienceSummary: Currently, the primary imaging methods used in clinical diagnosis are X-ray, computed tomography (CT), ultrasound, magnetic resonance imaging (MRI), PET-CT, etc.
Shuning Kong +4 more
doaj +1 more source
Social Science and Health Research: Growth at the National Institutes of Health
, 2004 Christine A. Bachrach, Ronald P. Abeles
openalex +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source