Results 141 to 150 of about 25,712,342 (298)
Health Sciences Libraries Annual Report, January-December 2016
, 2016 The Health Sciences Libraries at the University of Minnesota looks back at accomplishments in 2016.Health Sciences Libraries. (2016). Health Sciences Libraries Annual Report, January-December 2016. Retrieved from the University Digital Conservancy, https:
Health Sciences Libraries
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Celebrating nursing and midwifery: contributions to healthcare through research [PDF]
, 2006 National Institute of Health Sciences ...
National Institute of Health Sciences
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Mental health and well-being of African immigrant women in southern Alberta, Canada
The aim of this study was to delve into the experiences of African immigrant women in Southern Alberta and the ensuing impact on mental health. Employing an exploratory descriptive qualitative research design, semi-structured interviews were conducted ...
University of Lethbridge. Faculty of Health Sciences +1 more
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Annual Report, Health Sciences Libraries, 2015/2016
, 2016 In 2015/2016 we made our work visible through newly renovated spaces that support collaboration, learning, productivity, and study. We created new technology-enhanced spaces that support research and learning via our Virtual Reality Studio, Data ...
Health Sciences Libraries
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source