Results 81 to 90 of about 6,499,787 (384)

A multidimensional latent class Rasch model for the assessment of the Health-related Quality of Life [PDF]

open access: yesarXiv, 2012
The work describes a multidimensional latent class Rasch model and its application to data about the measurement of some aspects of Health-related Quality of Life and Anxiety and Depression in oncological patients.
arxiv  

The Scoop, Vol. 6 Issue 7, October 2019 [PDF]

open access: yes, 2019
Latest news and events from the Health Sciences Library in our monthly newsletter for October 2019.https://stars.library.ucf.edu/scoop-vol6/1005/thumbnail ...
Library, Health Sciences
core   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

A universal AutoScore framework to develop interpretable scoring systems for predicting common types of clinical outcomes

open access: yesSTAR Protocols, 2023
Summary: The AutoScore framework can automatically generate data-driven clinical scores in various clinical applications. Here, we present a protocol for developing clinical scoring systems for binary, survival, and ordinal outcomes using the open-source
Feng Xie   +12 more
doaj  

Multi-objective semi-supervised clustering to identify health service patterns for injured patients [PDF]

open access: yesarXiv, 2020
This study develops a pattern recognition method that identifies patterns based on their similarity and their association with the outcome of interest. The practical purpose of developing this pattern recognition method is to group patients, who are injured in transport accidents, in the early stages post-injury.
arxiv  

The Scoop, Vol. 5 Issue 11, February 2019 [PDF]

open access: yes, 2019
Latest news and events from the Health Sciences Library in our monthly newsletter for February 2019.https://stars.library.ucf.edu/scoop-vol5/1009/thumbnail ...
Library, Health Sciences
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

EpiTopics: A dynamic machine learning model to predict and inform non-pharmacological public health interventions from global news reports

open access: yesSTAR Protocols, 2022
Summary: Non-pharmacological interventions (NPIs) are important for controlling infectious diseases such as COVID-19, but their implementation is currently monitored in an ad hoc manner.
Zhi Wen   +5 more
doaj  

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