Results 81 to 90 of about 16,717,761 (430)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Methyl mercury concentrations in seafood collected from Zhoushan Islands, Zhejiang, China, and their potential health risk for the fishing community [PDF]

open access: yes, 2020
Seafood is an important exposure route for mercury, especially methyl mercury (MeHg). Therefore, we quantified MeHg concentrations in 69 species of seafood including fish, crustaceans and mollusks collected from Zhoushan Islands, China.
Khan, Anwarzeb   +7 more
core   +1 more source

Prevalence of Depression Among Health Sciences Students: Findings From a Public University in Malaysia

open access: yesJournal of Pharmacy and Bioallied Sciences, 2019
Background: High rates of psychological problems including depression among university students have been reported in various studies around the world.
Abdul Rahman M. Fata Nahas   +3 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Digital personal health libraries: a systematic literature review [PDF]

open access: yesarXiv, 2020
Objective: This paper gives context on recent literature regarding the development of digital personal health libraries (PHL) and provides insights into the potential application of consumer health informatics in diverse clinical specialties. Materials and Methods: A systematic literature review was conducted following the Preferred Reporting Items for
arxiv  

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Characterizing health informatics journals by subject-level dependencies: a citation network analysis [PDF]

open access: yesarXiv, 2018
Citation network analysis has become one of methods to study how scientific knowledge flows from one domain to another. Health informatics is a multidisciplinary field that includes social science, software engineering, behavioral science, medical science and others.
arxiv  

Prevalence of menstrual problems and their association with psychological stress in young female students studying health sciences

open access: yesSaudi Medical Journal, 2018
Objectives: To identify the prevalence of various menstrual problems in young females studying health sciences and to identify their association with academic stress.
N. Rafique, M. Al-Sheikh
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

CliMedBERT: A Pre-trained Language Model for Climate and Health-related Text [PDF]

open access: yesarXiv, 2022
Climate change is threatening human health in unprecedented orders and many ways. These threats are expected to grow unless effective and evidence-based policies are developed and acted upon to minimize or eliminate them. Attaining such a task requires the highest degree of the flow of knowledge from science into policy. The multidisciplinary, location-
arxiv  

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