Results 71 to 80 of about 10,145,051 (313)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Breaking the Chains of Tuberculosis: Quantifying the Effects of Literacy, Population Density, and Access to Improve Sanitation to Support Defense Health and Security in Indonesia

open access: yesJurnal Kedokteran Diponegoro, 2023
Background: Tuberculosis (TB) is a global health problem. It poses a significant burden worldwide, requiring urgent control measures and research for effective reduction especially in Indonesia.
Reinpal Falefi   +3 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Secure E-Health Platform [PDF]

open access: yes, 2020
Actualmente, Internet se ha convertido en una infraestructura de alojamiento de servicios a través de su interconexión de un gran número de objetos heterogéneos, ofreciendo así a los usuarios varios tipos de servicios implementados por diferentes sectores.
Karima Djouadi, Abdelkader Belkhir
openaire   +1 more source

Biodiversity and Global Health: Intersection of Health, Security, and the Environment

open access: yesHealth Security, 2021
B iodiversity is being lost at an alarming rate around the world, and many more species are at risk of extinction in the near future. Biodiversity is the measure of the variability of living organisms from genes to species to ecosystems and ecological ...
Andrew W Bartlow   +3 more
semanticscholar   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

UNDERSTANDING AUDIT METHODS TO ASSIST PLANNING ON PROGRAM EVALUATION: SHARING GAO’S EXPERIENCE ON NATIONAL HEALTH SECURITY PROGRAM

open access: yesJurnal Tata Kelola dan Akuntabilitas Keuangan Negara, 2017
BPK has a mandate to conduct performance audit for examining whether government agencies have implemented their critical programs in the possible aspects of efficiency, effectiveness or economy.
I Gede Sudi Adnyana
doaj  

Global Public Health Security [PDF]

open access: yesEmerging Infectious Diseases, 2007
The framework of the newly revised International Health Regulations is a key driver in the effort to strengthen global public health security. Unanimously agreed upon by the World Health Assembly on May 23, 2005, the regulations are the result of experience gained and lessons learned during the past 30 years.
Guénaël Rodier   +3 more
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Community Health Workers and Pandemic Preparedness: Current and Prospective Roles

open access: yesFrontiers in Public Health, 2019
Despite the importance of community health workers (CHWs) to health systems in resource-constrained environments, relatively little has been written about their contributions to pandemic preparedness.
Matthew R. Boyce, Rebecca Katz
doaj   +1 more source

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