Results 81 to 90 of about 17,124,068 (312)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Learning from partnership in the health services
, 2008 The need for measurement and evaluation of workplace partnership processes is explicitly stated in both the Health Services Partnership Agreement and the Action Plan for People Management.
Health Services National Partnership Forum (HSNPF)
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UNC Wilmington College of Health and Human Services 2022 impact report
, 2022 UNCW College of Health and Human Services' priorities, mission and values, strategic plan, degree progams, and ...
University of North Carolina, Wilmington. College of Health and Human Services
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BMC Public HealthBackground The number of frail older people is increasing. To alleviate poor health and improve quality of life, pre-frail and frail older people need to adhere to their medication.
Zixuan Hong +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Guidelines for medication management in Territory Health Services remote health centres
, 1995 This booklet is designed to give staff working in Territory Health Services Remote Health Centres an outline of what can be expected in dealing with medication in the centre and the pharmacy services that provide this medication.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
UNC Wilmington College of Health and Human Services 2023 impact report
, 2023 UNCW College of Health and Human Services' priorities, mission and values, strategic plan, degree progams, and ...
University of North Carolina, Wilmington. College of Health and Human Services
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source