Results 41 to 50 of about 19,960,223 (305)

Assisted Conception: Health Services and Evaluation [PDF]

International Journal of Technology Assessment in Health Care, 1991
AbstractComparison of assisted conception in Australia, the United Kingdom, and the United States indicates that further rapid growth in services is likely in many countries. Better data on pregnancy rates and the outcome of pregnancy, as well as standardized reporting of national results, are needed to monitor the effectiveness of treatment.
openaire   +2 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Indicators and Measurement Tools for Health Systems Integration: A Knowledge Synthesis

International Journal of Integrated Care, 2017
Background: Despite far reaching support for integrated care, conceptualizing and measuring integrated care remains challenging. This knowledge synthesis aimed to identify indicator domains and tools to measure progress towards integrated care.
Esther Suter, Nelly D. Oelke, Maria Alice Dias da Silva Lima, Michelle Stiphout, Robert Janke, Regina Rigatto Witt, Cheryl Van Vliet-Brown, Kaela Schill, Mahnoush Rostami, Shelanne Hepp, Arden Birney, Fatima Al-Roubaiai, Giselda Quintana Marques   +12 more
doaj   +1 more source

Exposing the impact of Citizens Advice Bureau services on health: a realist evaluation protocol [PDF]

, 2016
Introduction Welfare advice services can be used to address health inequalities, for example, through Citizens Advice Bureau (CAB). Recent reviews highlight evidence for the impact of advice services in improving people's financial position and ...
Hodgson, Philip, Lhussier, Monique, Forster, Natalie, Dalkin, Sonia, Carr, Susan   +4 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Perceptions and experiences of healthcare professionals of implementing the Organ Donation (Deemed Consent) Act in England during the Covid-19 pandemic

BMC Health Services Research
Context In May 2020 during the COVID-19 pandemic, England implemented a ‘soft’ opt-out system of consent to deceased organ donation. As part of a wider evaluation, this analysis focused on the perceptions of health care professionals, specifically their ...
Mustafa Al-Haboubi, Leah McLaughlin, Lorraine Williams, Jane Noyes, Stephen O’Neill, Paul Boadu, Jennifer Bostock, Nicholas Mays   +7 more
doaj   +1 more source

E-HEALTH SERVICES AND THEIR REQUIREMENTS EVALUATION

Business, Management and Education, 2010
E-health could be defined as the use of modern information technologies within the health care facilities in order to better satisfy expectations and needs of the patients, medical staff and administration. As the research shows economic profits exceed investments in the e-health three times. Studies in Lithuania in December of 2008 show that only 38 %
openaire   +3 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source