Results 61 to 70 of about 143,199,576 (301)

Serviços de atenção ao idoso e estratégias de cuidado domiciliares e institucionais

Revista Brasileira de Geriatria e Gerontologia
INTRODUÇÃO: As redes de atenção à saúde são fundamentais para assistir a população idosa em seus diversos aspectos. A assistência domiciliar, o Programa Acompanhante de Idosos da Secretaria Municipal da Saúde da cidade de São Paulo e as instituições de ...
Fernanda Pretti Chalet Ferreira, Luciana Orui Bansi, Sérgio Márcio Pacheco Paschoal   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Avaliação das instituições de longa permanência para idosos do município de Olinda-PE

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: Este trabalho se propõe a analisar a organização e funcionamento das instituições de longa permanência para idosos (ILPI) do município de Olinda-PE, através da aplicação do instrumento específico da Vigilância Sanitária, elaborado em 2007 ...
Barbara Helena de Brito Angelo, Débhora Isis Barbosa e Silva, Maria do Amparo Souza Lima   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Acute Myocardial Infarction in Older Adult Patients [PDF]

Geriatrics, Gerontology and Aging
OBJECTIVES: To assess clinical and coronary angiographic characteristics, previous medical history, and clinical course, by age group, in older adults after myocardial infarction who underwent primary percutaneous coronary intervention (pPCI).
Marcia Moura Schmidt, Cristina Klein Weber, Carlos Antonio Mascia Gottschall, Alexandre Schaan de Quadros   +3 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

National Council for the Aged: report on its second term of office, June 1984-March 1989.

, 1989
It was the 1968 Inter-Departmental Care of the Aged Report that first suggested the formation of a National Council for the Aged. This suggestion was implemented - in modified form - in June 1981 when the then Minister for Health, Dr.
National Council for the Aged
core  

Other titles: Kansas Department for Aging and Disability Services Behavioral Health Services Overview Behavioral Health Services Overview Overview of BHS Commission, Department for Aging and Disability Services Overview of Behavioral Health Services Commission, Department for Aging and Disability Services

, 2023
"January 10, 2023." Presentation before the Kansas Legislature, Senate Public Health & Welfare Committee, presented by Andy Brown, Commissioner, Behavioral Health Services, Kansas Department for Aging and Disability Services.Presentation reporting on the
Brown, Andy.
core  

Training for dementia care and support in rural and remote Australia: appraisals from a nationwide workforce survey

BMC Geriatrics
Background Dementia is a growing challenge to health and aged care worldwide and is the leading cause of disease burden in older Australians. High-quality person-centred care of people with dementia and support for their family caregivers require a ...
John A. Woods, Jessica Valentine, Kira Gusterson, Kathryn W. Fitzgerald, Katrina P. Fyfe, Myles Clarkson Fletcher, Mohammad Hamiduzzaman, Pascale Dettwiller, Anthony B. Fallon, Clare Dal Bon, Sarah E. Miles, Jo-Anne W. Rayner, Sandra C. Thompson   +12 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source