Results 81 to 90 of about 143,199,576 (301)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Leveraging health financing to strengthen mental health services in Ukraine

open access: yes, 2023
viii, 19 p.Ukraine has faced significant challenges in recent decades, including the effects of war since 2014 and the COVID-19 pandemic, each with profound impacts on population mental health; 2022 estimates suggest around 9.6 million people in Ukraine ...
World Health Organization. Regional Office for Europe
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

The magistrates' handbook of diversionary programs and services for alcohol and drug related offending / Alcohol and other drug services, Territory Health Services

open access: yes, 2000
This information handbook is a reference to the agencies that provide assessment and treatment programs for people whose offending I behaviour is linked with drug and alcohol use (1999 - 2000 edition).
Alcohol and Other Drugs Territory Health Services
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Models of general practitioner services in residential aged care facilities [PDF]

open access: yes, 2015
Describes different models for general practice care for patients in residential aged care facilities. Background Provision of timely and high-quality general practitioner (GP) services to patients in residential aged care facilities (RACFs) is ...
Richard Reed
core  

Prediction of oral diseases in care dependent older people

open access: yesBMC Oral Health
Background A large number of older people depend on others for help with their daily personal care, including oral health care. Nursing home and elder-care staff often face challenges identifying older people, who are exposed to or at an increased risk ...
Christina Andersen   +3 more
doaj   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

open access: yesFrontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen   +9 more
doaj   +1 more source

The relationship between quality of life, health and care transition: an empirical comparison in an older post-acute population

open access: yesHealth and Quality of Life Outcomes, 2012
Background The aim of this study was to explore, via empirical comparison, the relationship between quality of life, as measured by the ICECAP-O capability index (a new instrument designed to measure and value quality of life in older people), with both ...
Couzner Leah   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

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