Results 131 to 140 of about 1,367,738 (299)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Caregiver experiences and needs in pediatric rheumatic disease: a mixed-methods systematic review protocol

open access: yesSystematic Reviews
Introduction Understanding the genuine experiences and requirements of caregivers and implementing targeted interventions can have a positive impact on the physical and mental well-being of caregivers with children diagnosed with rheumatic diseases ...
Yuxuan Xiang   +5 more
doaj   +1 more source

Understanding the relationship between crime victimisation and mental health: a longitudinal analysis of population data [PDF]

open access: yes
Being a victim of violent crime has a damaging effect on mental health, particularly for women, according to this report. The needs and experiences of victims of crime have become increasingly recognised as an important aspect of criminal justice and ...
Karen Freeman, Nadine Smith
core  

Resolving unemployment [PDF]

open access: yes, 2014
There are 26 million unemployed in the EU, and no improvement is predicted for several years. But at the same time there are many unremitting needs in social housing, education and culture, nurseries, health, correct treatment of psychiatric patients ...
Roels, Frank
core   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Kualitas Pelayanan BPJS Di RSUD Kab. Karanganyar (Studi Kasus Pasien Rawat Inap) [PDF]

open access: yes, 2017
Social Security Agency of Health (BPJS) is a State-Owned Enterprises were specially commissioned by the government to administer health care benefits for all Indonesian people.
Paramashantaty, S. C. (Sastika)   +1 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Population, health, and nutrition : annual operational review for fiscal 1992 [PDF]

open access: yes
Population, health, and nutrition (PHN) lending decreased in fiscal 1992 from the record levels of fiscal 1991, in both the amount and the number of operations.
Brown, Stacye, Vaillancourt, Denise
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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