Results 41 to 50 of about 174,424 (254)
Some specific characteristics of the aging of the Brazilian population in different areas, states and communities all over the country, have shown significant variations.
Telarolli Junior Rodolpho +2 more
doaj
Introduction: The weaknesses of Guinea-Bissau’s health system have long been highlighted. The purpose of this study is to contribute with evidence for decision-making on the reform of the country’s healthcare map, by analyzing the availability and ...
André Beja +5 more
doaj +1 more source
Les tècniques computacionals de simulació han permès la introducció de metodologies de modelització per analitzar sistemes complexes a través d'experimentació virtual, i així avaluar l'impacte d'intervencions sobre els serveis sanitaris. La simulació d'esdeveniments discrets és una tècnica ben coneguda en la investigació operativa que s'ha desenvolupat
openaire +4 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Primary care and healthcare utilization among older Brazilians (ELSI-Brazil)
OBJECTIVE To characterize healthcare access and utilization among older Brazilians. METHODS Data are from the baseline wave of the Brazilian Longitudinal Study of Aging (ELSI-Brazil), which is a nationally representative, population-based cohort study
James Macinko +3 more
doaj +1 more source
Association between long working hours and unmet dental needs in wage workers
Background Many previous studies on the reasons behind unmet dental needs focus on economic issues. However, in this research, we aimed to investigate the relationship between long working hours and unmet dental needs while considering the influence of ...
Youngjin Choi, Inah Kim, Jaechul Song
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

