Results 41 to 50 of about 4,567,035 (352)

Patient perspectives on the promptness and quality of care of road traffic incident victims in Peru: a cross-sectional, active surveillance study [v1; ref status: indexed, http://f1000r.es/p2]

F1000Research, 2013
Background: Road injuries are the second-leading cause of disease and injury in the Andean region of South America. Adequate management of road traffic crash victims is important to prevent and reduce deaths and serious long-term injuries.
J Jaime Miranda, Edmundo Rosales-Mayor, D Alex Quistberg, Ada Paca-Palao, Camila Gianella, Pablo Perel, Luis Lopez, Diego Luna, Pablo Best, Luis Huicho, PIAT Working Group   +10 more
doaj   +1 more source

The rationale of e-health evaluation: The case of NHS Direct [PDF]

, 2009
An important area of research is that of the evaluation of e-health services. A holistic e-health evaluation framework should address the aspects that are hampering healthcare services from embracing the full potential of information and communication ...
Alalwany, H, Alshawi, S
core  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Lumboperitoneal shunt insertion without fluoroscopy guidance: Accuracy of placement in a series of 107 procedures [version 2; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
Background: Lumboperitoneal (LP) shunts were the mainstay of cerebrospinal fluid diversion therapy for idiopathic intracranial hypertension (IIH).
Sabah Al-Rashed, Haider Kareem, Neeraj Kalra, Linda D'Antona, Mouness Obeidat, Bhavesh Patel, Ahmed Toma   +6 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Blockchain protocols in clinical trials: Transparency and traceability of consent [version 4; referees: 1 approved, 2 approved with reservations, 2 not approved]

F1000Research, 2017
Clinical trial consent for protocols and their revisions should be transparent for patients and traceable for stakeholders. Our goal is to implement a process allowing for collection of patients’ informed consent, which is bound to protocol revisions ...
Mehdi Benchoufi, Raphael Porcher, Philippe Ravaud   +2 more
doaj   +1 more source

Student Mental Health Curriculum for Teachers: A Proposal [PDF]

, 2011
It is estimated that only one fifth of children who need mental health services receive them, primarily through school-based services (Burns et al., 1995).
Jones, Weneaka D
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A promising approach to scale up health care improvements in low-and middle-income countries: the Wave-Sequence Spread Approach and the concept of the Slice of a System [v1; ref status: indexed, http://f1000r.es/37o]

F1000Research, 2014
There are several examples of successes in improving health care. However, many of these tend to remain limited to the sites they were originally developed in.
M. Rashad Massoud, Nana Mensah-Abrampah
doaj   +1 more source

Benefits from clinicians and healthcare organisations engaging in research [PDF]

, 2015
In Editor’s Choice, Godlee supports and re-emphasises the positive points about National Institute for Health Research (NIHR) clinical research networks that are made in Gulland’s article.1 2 We welcome this support for research networks and for the part
Boaz, A, Hanney, S, Jones, TH, Soper, B
core   +1 more source