Results 61 to 70 of about 1,874,846 (315)

Evaluating healthcare priority setting at the meso level: A thematic review of empirical literature [version 2; referees: 3 approved]

Wellcome Open Research, 2018
Background: Decentralization of health systems has made sub-national/regional healthcare systems the backbone of healthcare delivery. These regions are tasked with the difficult responsibility of determining healthcare priorities and resource allocation ...
Dennis Waithaka, Benjamin Tsofa, Edwine Barasa   +2 more
doaj   +1 more source

Investigating the utilization of radiological services by physician patients: A population-based cohort study in Taiwan

, 2013
[[abstract]]Background: Advances in radiology technology have contributed to a substantial increase in utilization of radiology services. Physicians, who are well educated in medical matters, would be expected to be knowledgeable about prudent or ...
Wu, CY;Hu, HY;Chen, L;Huang, N;Chou, YJ;Li, CP
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Outcomes of prolonged mechanic ventilation: a discrimination model based on longitudinal health insurance and death certificate data

, 2012
[[abstract]]ABSTRACT: BACKGROUND: This study investigated prognosis among patients under prolonged mechanical ventilation (PMV) through exploring the following issues: (1) post-PMV survival rates, (2) factors associated with survival after PMV, and (3 ...
Lu, HM;Chen, L;Wang, JD;Hung, MC;Lin, MS;Yan, YH;Chen, CR;Fan, PS;Huang, LC;Kuo, KN
core   +1 more source

Accounting for Research – the Difficulties Posed for User-Centred Research [PDF]

, 2006
When public money is invested in research it is necessary to have in place accounting systems that demonstrate its value. By this we mean its social as much as its economic value to society.
Minogue, Virginia, Grant, Gordon, Walsh, Mike, Courtney, Duncan, King, Sarah, Shields, Graham, Walsh, Michael   +6 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Breaking a Guinness World Record on Hand Sanitizing Relay, initiating a call for vital research in overcoming campaign fatigue for hand hygiene [v1; ref status: indexed, http://f1000r.es/4gb]

F1000Research, 2014
Hand hygiene has been shown to be effective in significantly reducing hospital acquired infections for many years. However it is difficult to maintain and enhance compliance with hand hygiene guidelines. In Hong Kong, we previously reported a strategy to
Wing Hong Seto, Kwok-Hung Li, Christina Woon Yee Cheung, Patricia Tai Yin Ching, Benjamin J. Cowling   +4 more
doaj   +1 more source

Primary care management of chronic insomnia: a qualitative analysis of the attitudes and experiences of Australian general practitioners

BMC Family Practice, 2021
Background Chronic insomnia is a highly prevalent disorder, with ten to thirty percent of Australian adults reporting chronic difficulties falling asleep and/or staying asleep such that it causes significant daytime impairment. Current Australian general
Jenny Haycock, Nicole Grivell, Anne Redman, Bandana Saini, Andrew Vakulin, Leon Lack, Nicole Lovato, Alexander Sweetman, Nicholas Zwar, Nigel Stocks, Oliver Frank, Sutapa Mukherjee, Robert Adams, R. Doug McEvoy, Elizabeth Hoon   +14 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

INTEGRATED HEALTH SERVICE DELIVERY: WHY AND HOW?

National Journal of Medical Research, 2013
Integrated service delivery is an approach of combining services of multiple interrelated diseases to increase overall efficiency of the health system and patient convenience.
Satya Ranjan Lenka, Bitra George
doaj