Results 71 to 80 of about 1,874,846 (315)

Has incentive payment improved venous thrombo-embolism risk assessment and treatment of hospital in-patients? [v1; ref status: indexed, http://f1000r.es/8k]

F1000Research, 2013
This paper focuses on financial incentives rewarding successful implementation of guidelines in the UK National Health Service (NHS). In particular, it assesses the implementation of National Institute for Health and Clinical Excellence (NICE) venous ...
Sue Child, Rod Sheaff, Olga Boiko, Alice Bateman, Christian A Gericke   +4 more
doaj   +1 more source

An Introduction to Health Services Research

Electronic Notes in Discrete Mathematics, 1999
Abstract Analysts performing health services research must analyze large observational databases of real world medical care. These databases provide important information about real world patient outcomes, but confound the evaluation of therapies since patients and physicians select the treatment assignment.
openaire   +1 more source

New directions in European public health research:report of a workshop [PDF]

, 2007
Public health draws from a range of academic disciplines, social, medical and statistical, and answers questions relevant to improving the health of populations.
Álvarez-Dardet, Carlos, Groot, W., Groot, Wim, Alvarez-Dardet, C., Groenewegen, P, Clarke, A, McCarthy, M, Groenewegen, Peter, McCarthy, M., Delnoij, D., Alvarez-Dardet, C, McCarthy, Mark, Groenewegen, Peter P., Groot, W, Sogoric, S, Sogoric, Selma, Delnoij, D, Sogoric, S., Delnoij, Diana, Groenewegen, P., Clarke, Aileen, Clarke, A.   +21 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A promising approach to scale up health care improvements in low-and middle-income countries: the Wave-Sequence Spread Approach and the concept of the Slice of a System [v2; ref status: indexed, http://f1000r.es/3sa]

F1000Research, 2014
There are several examples of successes in improving health care. However, many of these remain limited to the sites at which they were originally developed.
M. Rashad Massoud, Nana Mensah-Abrampah
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Patient predictors of poor drug sensitive tuberculosis treatment outcomes in Kyiv Oblast, Ukraine [version 2; peer review: 2 approved, 1 approved with reservations]

F1000Research, 2018
Background: Ukraine has high rates of poor treatment outcomes among drug sensitive tuberculosis (DSTB) patients, while global treatment success rates for DSTB remain high.
Omowunmi Aibana, Andrej Slavuckij, Mariya Bachmaha, Viatcheslav Krasiuk, Natasha Rybak, Timothy P. Flanigan, Vasyl Petrenko, Megan B. Murray   +7 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bridge / Foundation for Health Services Research

, 1998
no. 3-5; 7-18, 1989-1998An international newsletter linking the producers and users of health systems research and clinical epidemiologyCeased ...
Association for Health Services Research, WHO. Health Systems Research and Development Program   +1 more
core  

Increasing clinical, community, and patient-centered health research

, 2013
The report “Multiple Chronic Conditions: A Strategic Framework,” which was developed by the U.S. Department of Health & Human Services (HSS), has identified as one of the key goals for improving health and the provision of healthcare for people with ...
Jose M. Valderas, Valderas, Jose M.
core   +1 more source