Results 71 to 80 of about 888,949 (266)

Association between social skills and mental health outcomes in Health Science Residents in Brazil.

PLoS ONE
Residency programs play a crucial role in the development and technical training of young health professionals. However, mental health issues such as psychological distress, anxiety, and depression are prevalent, often influenced by work satisfaction and
Carina Rodrigues da Silva, Andreia Gonçalves Arruda, João Wellinton Pletti, Ana Amélia Domingues Gomes, Thaís Rabelo Dos Santos-Doni, Rafael Felipe da Costa Vieira, Alexandre Coutinho Antonelli, Dagma Venturini Marques Abramides, Alexandre Redson Soares da Silva   +8 more
doaj   +1 more source

Showcasing the contribution of social sciences to health policy and systems research

International Journal for Equity in Health, 2018
Background This Special Issue represents a critical response to the frequent silencing of qualitative social science research approaches in mainstream public health journals, particularly in those that inform the field of health policy and systems ...
Stephanie M. Topp, Kerry Scott, Ana Lorena Ruano, Karen Daniels   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Theoretical background of healthcare management in the conditions of social and economic instability [PDF]

Саратовский научно-медицинский журнал, 2015
Purpose: to develop fundamental basis of science based healthcare management in social and economic instability. Public health state (1998-2008, selected region) was characterized by cardiovascular health parameters (Code IX, ICD-10).
Shuldyakov V.A., Chernenkov Yu.V., Denisova Т.Р.   +2 more
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A practical framework for selecting and interpreting regression models for binary outcomes in social science and public health studies

Discover Social Science and Health
In social science and public health research, binary outcomes are common (e.g., disease presence, mental health status, health behaviors), as they simplify complex constructs into clear categories, facilitating interpretation, communication, and ...
Thinh Toan Vu
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Welcome to Discover Social Science and Health [PDF]

Discover Social Science and Health, 2021
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source