Results 91 to 100 of about 20,558,778 (308)

Socioeconomic Status and Health: Dimensions and Mechanisms [PDF]

open access: yes
This paper reviews the evidence on the well-known positive association between socioeconomic status and health. We focus on four dimensions of socioeconomic status -- education, financial resources, rank, and race and ethnicity -- paying particular ...
Adriana Lleras-Muney   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Comparison of health-related quality of life measures in chronic obstructive pulmonary disease

open access: yesHealth and Quality of Life Outcomes, 2011
Background The aims of this study were: (1) to compare the discriminative ability of a disease-specific instrument, the St. George's Respiratory Questionnaire (SGRQ) to generic instruments (i.e., EQ-5D and SF-36); and (2), to evaluate the strength of ...
Lee Todd A   +2 more
doaj   +1 more source

Local health district oveview report 2003-2004 Utah Health Status Survey Report

open access: yes, 2005
Provides infomration on 18 health measures from the 2003-2004 health status survey, plus a section comparing age-adjusted and crude rates of these same 18 ...
Utah. Office of Public Health Assessment
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Portfolio Choice and Health Status [PDF]

open access: yes
This paper analyzes the role that health status plays in household portfolio decisions using data from the Health and Retirement Study. The results indicate that health is a significant predictor of both the probability of owning different types of ...
Harvey S. Rosen, Stephen Wu
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Damage evaluation and resistance enhancement technologies for highway tunnels under high-power fire conditions

open access: yesCase Studies in Thermal Engineering
The operation of highway tunnels involves numerous complex challenges, which become particularly pronounced during extreme disasters such as fires. This study takes the Qinling Tiantai Mountain Highway Tunnel as the engineering background and focuses on ...
Yufeng Sun   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Special feature on socioeconomic status and health [PDF]

open access: yes
"Health, United States, 2011 is the 35th report on the health status of the Nation and is submitted by the Secretary of the Department of Health and Human Services to the President and the Congress of the United States in compliance with Section 308 of ...

core  

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