Results 81 to 90 of about 8,269,895 (309)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The moderating effect of physical activity in the relationship between sleep quality and BMI in adults with overweight and obesity

Frontiers in Sports and Active Living
Inadequate sleep quality is a significant risk factor for overweight and obesity, which in turn may predispose individuals to adverse health outcomes.
Letizia Galasso, Ramona De Amicis, Ramona De Amicis, Lucia Castelli, Andrea Ciorciari, Andrea Ciorciari, Antonino Mulè, Alberto Battezzati, Alberto Battezzati, Simona Bertoli, Simona Bertoli, Andrea Foppiani, Andrea Foppiani, Alessandro Leone, Alessandro Leone, Fabio Esposito, Angela Montaruli, Eliana Roveda   +17 more
doaj   +1 more source

Impact of Schoolchildren’s Health Status on Their Academic Performance

Zdorovʹe Rebenka, 2014
The article presents the results of a comparative analysis of health status and factors of psycho-physical development of children of middle and senior school age.
V.P. Nedilko, S.A. Rudenko
doaj   +1 more source

The impact of health on poverty: Evidence from the South African integrated family survey [PDF]

This paper examines the impact of health status on poverty status, accounting for the endogeneity of health status. Using exogenous measures of health status from the South African Integrated Health Survey, we instrument for health status while allowing ...
Malcolm Keswell, Susan Godlonton
core   +1 more source

Socio-demographic disparity in Oral Health among the Poor: A Cross Sectional Study of Early Adolescents in Kilwa District, Tanzania. [PDF]

, 2010
There is a lack of studies considering social disparity in oral health emanating from adolescents in low-income countries. This study aimed to assess socio-demographic disparities in clinical- and self reported oral health status and a number of oral ...
Mashoto, Kijakazi O, Astrom, Anne N, Skeie, Marit S, Masalu, Joyce R   +3 more
core   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Comparison of health-related quality of life measures in chronic obstructive pulmonary disease

Health and Quality of Life Outcomes, 2011
Background The aims of this study were: (1) to compare the discriminative ability of a disease-specific instrument, the St. George's Respiratory Questionnaire (SGRQ) to generic instruments (i.e., EQ-5D and SF-36); and (2), to evaluate the strength of ...
Lee Todd A, Yang Yoojung, Pickard A Simon   +2 more
doaj   +1 more source