THEY SAY THAT THEY ARE HEALTHY, BUT ARE THEY? HEALTH PERCEPTIONS IN THE U.S. [PDF]
Public health initiatives are the result of strategies developed to address current health issues facing a population that are posing a significant concern to the public. This concern is primarily driven by the economics of health care.
Amanor-Boadu, Vincent, Ross, Kara L.
core +1 more source
Assessment of oral health status and practice among diabetic and nondiabetic participants. [PDF]
Almeneessier AS+5 more
europepmc +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Health status in the era of digital transformation and sustainable economic development. [PDF]
Bocean CG, Vărzaru AA.
europepmc +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Health Status of Tsimihety Women: Sexually Transmitted Infections and Schistosomiasis, Northern Madagascar. [PDF]
Kasprowicz D+2 more
europepmc +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
The impact of physical activity on adolescent mental health status: the mediating effect of school adaptation. [PDF]
Zhang M, Gu C, Zeng H, Yi X.
europepmc +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source