Results 121 to 130 of about 8,269,895 (309)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

How people rate their own health: a nationwide study from Iran

open access: yesPayesh, 2011
Objective (s): Little is known about self-reported health in developing countries such as Iran. As part of a large study on health perception in Iran this was investigated.Methods: This was a nationwide cross sectional study.
Maryam Vahdaninia   +9 more
doaj  

Insurance, Health, and the Utilization of Medical Services [PDF]

open access: yes
Most data sets indicate a positive correlation between having health insurance and good health, and between having health insurance and utilizing health care services. Yet the direction of causality is not at all clear.
Harvey S. Rosen, Jonathan Meer
core  

Adolescent Health Services: Missing Opportunities [PDF]

open access: yes, 2008
Examines the status of adolescents' health and health services, including critical needs, promising models, and components for improving disease prevention and health promotion.
Jennifer Appleton Gootman   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Role of Child Health and Economic Status in Educational, Health and Labour Market Outcomes in Young Adulthood [PDF]

open access: yes
The Ontario Child Health Study provides the first opportunity in Canada to assess directly the relationship between socio-economic and health status in childhood and levels of completed schooling, health status and labour market success in young ...
Martin Dooley, Paul Contoyannis
core  

The SES health gradient on both sides of the Atlantic [PDF]

open access: yes, 2006
In this paper we investigate the size of health differences that exist among men in England and the United States and how those differences vary by Socio-Economic Status (SES) in both countries.
Banks, J.   +3 more
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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