Results 121 to 130 of about 8,062,995 (308)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
How people rate their own health: a nationwide study from Iran
Payesh, 2011 Objective (s): Little is known about self-reported health in developing countries such as Iran. As part of a large study on health perception in Iran this was investigated.Methods: This was a nationwide cross sectional study.
Maryam Vahdaninia +9 more
doaj
The Stability of Self Assessed Health Status [PDF]
The use of self assessed health status as a measure of health is common in empirical research. We analyse a unique Australian survey in which a random sub-sample of respondents answer a standard self assessed health question twice -- before and after an ...
Steven Kennedy, Thomas F. Crossley
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Adolescent Health Services: Missing Opportunities [PDF]
, 2008 Examines the status of adolescents' health and health services, including critical needs, promising models, and components for improving disease prevention and health promotion.
Jennifer Appleton Gootman +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Productive Benefits of Health: Evidence from Low-Income Countries [PDF]
Various household survey indicators of adult nutrition and health status are analyzed as determinants of individual wages. However, survey indicators of health status may be heterogeneous, or a combination of health human capital formed by investment ...
T. Paul Schultz
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Creating Community Environments That Promote Comprehensive Health and Wellness [PDF]
, 2006 Describes the impact of Hurricanes Katrina and Rita on the health of the residents of Arkansas, Louisiana, and Mississippi. Outlines strategies to identify effective programs designed to reduce health disparities and improve health status in the ...
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