Results 161 to 170 of about 2,765,279 (315)

Subjective knowledge of school adolescents about the health effects of smoking and association with smoking status

, 2021
Leonardo Essado Rios, Maria do Carmo Matias Freire   +1 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Secular trends in incidence, survival, and health status at diagnosis of dementia in Sweden, 2007-2022. [PDF]

Alzheimers Res Ther
Ding M, Ek S, Yang F, Fang F, Schmidt-Mende K, Modig K.   +5 more
europepmc   +1 more source

Assessment of the health status in pharmaceutical workers

Yu.G. Nagornyak, T.A. Kanakina, Evgenia A. Ruzlyaeva, Vasiliy A. Fokin, A. V. Ratkin   +4 more
openalex   +2 more sources

Body Composition and Health Status of Female Physical Education Students During the Summer Outdoor Activities Camp On-Site at Gazivode Lake

, 2023
Jasna Popović, Miloš Popović, Tatjana Popović Ilić, Ružena Popović, Vladimir Miletić, Tijana Purenović- Ivanović   +5 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Effect of Preinfection Health Status on COVID-19 Severity and Cognitive Function. [PDF]

Brain Behav
Yuan K, Xian W, Lin L, Su F, Huang F, Sheng W, Wu W.   +6 more
europepmc   +1 more source

GREATER DISEASE BURDEN, GREATER RISK? EXPLORING COGNITIVE CHANGE AND HEALTH STATUS AMONG OLDER BLACKS [PDF]

, 2018
Desiree Byrd, Roland J. Thorpe, K Whitfield   +2 more
openalex   +1 more source

Supplemental file 1: Sexual health risk indicators and their associations with caries status and gingival health of adolescents resident in sub-urban South-West Nigeria

, 2021
Morẹ́nikẹ́ Oluwátóyìn Foláyan, Maha El Tantawi, Randa Yassin, Olaniyi Arowolo, Nadia A. Sam‐Agudu   +4 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source