Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Sex differences in coronary disease health Status outcomes: the ISCHEMIA trial. [PDF]
Eur Heart J Qual Care Clin OutcomesGrodzinsky A +11 more
europepmc +1 more source
Summary health statistics for U.S. adults; National Health Interview Survey, 2001 [PDF]
OBJECTIVES: This report presents health statistics from the 2001 National Health Interview Survey for the civilian noninstitutionalized adult population classified by sex, age, race and Hispanic origin, poverty status, and region of residence for chronic
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Development and Validation of a Subjective Health Status Scale for Collegiate Athletes. [PDF]
Sports (Basel)Tatsuta W +4 more
europepmc +1 more source
Socioeconomic Status and Health Outcomes in a Developing Country [PDF]
While the relationship between socioeconomic status (SES) and health is well documented for developed countries, less evidence has been presented for developing countries.
Ignacio Correa-Valez +3 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Relationship of rotating-shift work with lifestyle and health status of hospital employees. [PDF]
PLOS Glob Public HealthAlou-Soler MA +4 more
europepmc +1 more source
Social heterogeneity in self-reported health status and measurement of inequalities in health [PDF]
This study aims to analyse the impact of the measurement of health status on socioeconomic inequalities in health. A MIMIC model with structural equations is used to create a latent variable of health status from four health indicators: self-assessed ...
Marion Devaux +3 more
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