Results 61 to 70 of about 12,028,587 (365)

Efficacy and Safety of Semaglutide for the Management of Obese Patients With Type 2 Diabetes and Chronic Heart Failure in Real-World Clinical Practice

Frontiers in Endocrinology, 2022
BackgroundThe impact of glucagon-like peptide-1 receptor agonists on patients with heart failure has not been fully described. Our main objective was to evaluate the safety and clinical and glycemic efficacy of once-weekly semaglutide in obese patients ...
Luis M. Pérez-Belmonte, Luis M. Pérez-Belmonte, Luis M. Pérez-Belmonte, Jaime Sanz-Cánovas, María D. García de Lucas, Michele Ricci, Beatriz Avilés-Bueno, Lidia Cobos-Palacios, Miguel A. Pérez-Velasco, Almudena López-Sampalo, M. Rosa Bernal-López, M. Rosa Bernal-López, Sergio Jansen-Chaparro, José P. Miramontes-González, José P. Miramontes-González, Ricardo Gómez-Huelgas, Ricardo Gómez-Huelgas   +16 more
doaj   +1 more source

Health status and health service utilization in remote and mountainous areas in Vietnam

Health and Quality of Life Outcomes, 2016
BackgroundSelf-rated health status and healthcare services utilization are important indicators to evaluate the performance of health system. In disadvantaged areas, however, little is known about the access and outcomes of health care services.
B. Tran, L. H. Nguyen, V. M. Nong, C. Nguyen   +3 more
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Relationship Between Depressive Symptoms and Health Status in Peripheral Artery Disease: Role of Sex Differences

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The association of depressive symptoms with health status in peripheral artery disease (PAD) is understudied. No reports of differential impact on women have been described.
Qurat‐ul‐ain Jelani, Carlos Mena‐Hurtado, Matthew Burg, Robert Soufer, Kensey Gosch, Philip G. Jones, John A. Spertus, Basmah Safdar, Kim G. Smolderen   +8 more
doaj   +1 more source

Health status

Health at a Glance, 2018
HEALTH STATUS .......................................................................................................................................................

semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Relationship between Health Literacy, Health-Related Behaviors and Health Status: A Survey of Elderly Chinese

International Journal of Environmental Research and Public Health, 2015
Background: Despite the large volume of research dedicated to health-related behavior change, chronic disease costs continue to rise, thus creating a major public health burden.
Yongbing Liu, Liu Liu, Yanfei Li, Yan-li Chen   +3 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source