Results 91 to 100 of about 582,509 (334)

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Interactive effect of eight weeks combined training and curcumin consumption on serum levels of interleukin-12 and some anthropometric indicators in obese sedentary woman

open access: yesFiyz̤, 2020
Background: Activity has turned away from the human body by machine life and has replaced with obesity. This study aimed to investigate the interactive effect of eight weeks combined training and curcumin consumption on serum levels of interleukin-12 and
Mirmahzoon M   +2 more
doaj  

The Autoregressive Structural Model for analyzing longitudinal health data of an aging population in China [PDF]

open access: yesarXiv, 2019
We seek to elucidate the impact of social activity, physical activity and functional health status (factors) on depressive symptoms (outcome) in the China Health and Retirement Longitudinal Study (CHARLS), a multi-year study of aging involving 20,000 participants 45 years of age and older.
arxiv  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Derivation of indices of socioeconomic status for health services research in Asia

open access: yesPreventive Medicine Reports, 2015
Environmental contexts have been shown to predict health behaviours and outcomes either directly or via interaction with individual risk factors. In this paper, we created indexes of socioeconomic disadvantage (SEDI) and socioeconomic advantage (SAI) in Singapore to test the applicability of these concepts in an Asian context. These indices can be used
Arul Earnest   +7 more
openaire   +4 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Evaluation of Performance Indicators of Qazvin Educational and Medical Centers before and after the Implementation of the Health System Transformation Plan: Interrupted Time Series Analysis

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021
Background and Objectives: The present study was conducted to investigate the status of performance indicators in hospitals affiliated to Qazvin University of Medical Sciences before and after the implementation of the transformation plan.
Bahman Ghasemzadeh   +3 more
doaj  

Comparison of Health Status Indicators with Multidimensional Scaling and The Multi Objective Optimization by Ratio Analysis

open access: yesSağlık ve Hemşirelik Yönetimi Dergisi, 2018
INTRODUCTION: Health is important in determining the development and development levels of countries. One of the goals of the country's health system is to raise the health level of the community as much as possible.
Canser Boz, Emrah Önder, Nihat Taş
doaj   +1 more source

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