Results 151 to 160 of about 2,672,635 (325)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Can Micro Health Insurance Reduce Poverty? Evidence from Bangladesh [PDF]

open access: yes, 2010
This paper examines the impact of micro health insurance on poverty reduction in rural areas of Bangladesh. The research is based on household level primary data collected from the operating areas of the Grameen Bank during 2006.
Hamid, S.A., Mosley, P., Roberts, J.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

State of Our Estuaries 2006 [PDF]

open access: yes, 2006
The 2006 State of the Estuaries Report includes twelve indicators intended to report on the health and environmental quality of New Hampshire’s estuaries.
Piscataqua Region Estuaries Partnership
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

GROWING UP IN IRELAND KEY FINDINGS: COHORT ’98 AT 20 YEARS OLD IN 2018/19 NO. 2 PHYSICAL HEALTH AND DEVELOPMENT [PDF]

open access: yes, 2019
This Key Findings report presents summary information on the lives and circumstances of the 20-year-olds from the fourth wave of interviews with Growing Up in Ireland’s older Cohort ’98 between August 2018 and June 2019.
Authors, No
core  

Disparities in Life Expectancy Across US Counties Linked to County Social Factors, 2009 Community Health Status Indicators (CHSI)

open access: yesJournal of Racial and Ethnic Health Disparities, 2014
Ben Davids   +3 more
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Evolução de condicionantes socioeconômicas da saúde na infância na cidade de São Paulo (1984-1996)

open access: yesRevista de Saúde Pública
OBJETIVO: Descrever a evolução de condicionantes socioeconômicas da saúde na infância, com base nas informações extraídas de dois inquéritos domiciliares realizados nos anos de 1984/85 e 1995/96, na cidade de São Paulo, SP.
Carlos Augusto Monteiro   +1 more
doaj  

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