Results 181 to 190 of about 849,913 (310)

Tendência secular da anemia na infância na cidade de São Paulo (1984-1996)

open access: yesRevista de Saúde Pública
OBJETIVO: Estimar a prevalência e a distribuição social da anemia na infância, estabelecer a tendência secular dessa enfermidade e analisar sua determinação, com base em dados coletados por dois inquéritos domiciliares realizados na cidade de São Paulo ...
Carlos Augusto Monteiro   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Assessing the efficiency of HIV prevention interventions in Kenya – the ORPHEA Project

open access: yesAnnals of Global Health, 2015
R. Wamai   +12 more
doaj   +1 more source

Anxiolytic Medication Use in Low- Middle- and High-Income Countries: A World Mental Health Surveys Report. [PDF]

open access: yesHum Psychopharmacol
Stein DJ   +31 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

National Health and Nutrition Examination Survey 1999\u20132016 survey content brochure

open access: yes
The Survey Content Brochure is a summary of the available 1999\u20132016 NHANES data.The National Health and Nutrition Examination Survey (NHANES) is a program of studies designed to assess the health and nutritional status of adults and children in the ...

core  

Tendência secular da doença respiratória na infância na cidade de São Paulo (1984-1996)

open access: yesRevista de Saúde Pública
OBJETIVO: Estimar a prevalência e a distribuição social da doença respiratória na infância, estabelecer a tendência secular dessa enfermidade e analisar sua determinação, com base nos dados coletados por dois inquéritos domiciliares realizados na cidade ...
Maria Helena D'Aquino Benicio   +3 more
doaj  

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