Results 211 to 220 of about 2,121,296 (312)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Predictors and barriers to minimally adequate treatment among treated individuals with mental disorders: results from the World Mental Health Surveys. [PDF]

Int J Ment Health Syst
Pozuelo JR, Vigo DV, Kazdin AE, Harris MG, Stein DJ, Viana MC, Hwang I, Kessler TL, Manoukian SM, Sampson NA, Aguilar-Gaxiola S, Alonso J, Andrade LH, Ayinde OO, Bruffaerts R, Bunting B, Caldas-de-Almeida JM, Chardoul S, de Girolamo G, Domenech C, Gureje O, Karam EG, Kiejna A, Kovess-Masfety V, Medina-Mora ME, Moskalewicz J, Navarro-Mateu F, Nishi D, Piazza M, Posada-Villa J, Scott KM, Ten Have M, Torres Y, Vladescu C, Kessler RC, World Mental Health Survey collaborators.   +35 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Predictors and prevalence of self-reported sexually transmitted infections among pregnant women in East Africa: evidenced by demographic and health surveys. [PDF]

BMC Infect Dis
Mankelkl G, Abdu SM, Assefa EM, Kassaw AB, Abebe G, Belete M, Tareke AA, Alem A, Bihonegn MD, Abdu H, Abebe MS, Geto Z, Gedefie A, Kinfe B.   +13 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Beyond survey design: Lessons from conducting the National Adolescent Mental Health Surveys. [PDF]

Child Adolesc Psychiatry Ment Health
Erskine HE, Wado YD, Loi VM, Hoa DTK, Wahdi AE, Li M, Scott JG.   +6 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Discharge time from healthcare facilities after birth in Tanzania : a secondary analysis of demographic and health surveys from 2015 to 16 and 2022. [PDF]

BMC Health Serv Res
Semaan A, Apers L, Kikula A, van den Akker T, Pembe AB, Beňová L, Housseine N.   +6 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Hypertension in women of reproductive age: a cross-sectional analysis of prevalence and risk factors across 21 low-income and middle-income countries using Demographic and Health Surveys (2013-2023). [PDF]

BMJ Open
Andriani H, Arsyi M, Andhisa CS, Mohd Hairi F.   +3 more
europepmc   +1 more source