Results 261 to 270 of about 12,161,547 (411)

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The association between psychotic experiences and disability: results from the WHO World Mental Health Surveys

open access: yesActa Psychiatrica Scandinavica, 2017
F. Navarro-Mateu   +57 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Fatores associados ao consumo de frutas e hortaliças no Brasil, 2006

open access: yesRevista de Saúde Pública
OBJETIVO: Estimar a freqüência do consumo de frutas e hortaliças e fatores associados. MÉTODOS: Foram estudados 54.369 indivíduos com idade >18 anos, entrevistados pelo sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por ...
Patricia Constante Jaime   +3 more
doaj  

Antenatal care and breastfeeding practices in Sub-Saharan Africa: an analysis of demographic and health surveys. [PDF]

open access: yesBMC Pregnancy Childbirth
Olapeju B   +5 more
europepmc   +1 more source

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