Results 181 to 190 of about 39,234,544 (355)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Sistema de salud de Honduras The health system of Honduras

Salud Pública de México, 2011
En este trabajo se describe el sistema de salud de Honduras, incluyendo los retos que enfrenta, su estructura y cobertura, su financiamiento, los recursos con los que cuenta y las actividades de rectoría que en él se desarrollan.
Juan Luis Bermúdez-Madriz, María del Rocío Sáenz, Jorine Muiser, Mónica Acosta   +3 more
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Actioning the Learning Health System: An Applied Framework for Integrating Research into Health Systems

SSM - Health Systems
Robert J. Reid, Walter P. Wodchis, Kerry Kuluski, Nakia K. Lee-Foon, J. Lavis, Laura C Rosella, Laura Desveaux   +6 more
semanticscholar   +1 more source

Acute viral myositis complicated by rhabdomyolysis: a sole manifestation of COVID-19 infection

Journal of Community Hospital Internal Medicine Perspectives, 2021
Mohsin Sheraz Mughal, Ikwinder Preet Kaur, Reem Alhashemi, Rameez Rehman, Doantrang Du   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Health Information Systems [PDF]

Yearbook of Medical Informatics, 2005
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The U.S. health system vulnerabilities. [PDF]

BMC Health Serv Res
Brantly ND.
europepmc   +1 more source

Systemic health screening [PDF]

British Dental Journal, 2012
openaire   +2 more sources