Results 161 to 170 of about 32,527,248 (315)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Slovenia: health system review
207 p.This analysis of the Slovene health system reviews recent developmentsin organization and governance, health financing, health care provision,health reforms and health system performance.
Panteli, Dimitra +9 more
core
Toward a Smart Learning Health System: An Ontology-Based Framework. [PDF]
Ma M, Yu P, Hickman LD.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Health system strategies for adaptation to drought: A global scoping review. [PDF]
Khosravifar A +8 more
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Tajikistan: health system review
154 p.The Health Systems in Transition (HiT) profiles are country-based reportsthat provide a detailed description of a health system and of policyinitiatives in progress or under development.
Rechel, Bernd +3 more
core
A multidimensional classification of assistive technology for health system integration. [PDF]
Sharma HK +6 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

