Results 191 to 200 of about 39,234,544 (355)

Privatization of health sector in ex socialist states [PDF]

open access: yes
Privatization of health care system in ex socialist states is one of the most controversial political and legal questions. On one part there is a widening discrepancy between the costs of health care system and the capability of public finances to cover ...
Strazisar, Borut
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Health information system.

open access: yesEinstein (Sao Paulo, Brazil), 2013
de Souza, Valéria Pinheiro   +2 more
openaire   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

open access: yesActa Neuropathologica, 2016
D. Louis   +9 more
semanticscholar   +1 more source

Pediatric Skin and Soft Tissue Infection Antibiogram and Antibiotics Prescription Pattern in the Pediatric Emergency and In-Patient Settings

open access: yesJournal of Scientific Innovation in Medicine, 2019
Matthias Manuel   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Disability inclusion in the Brazilian health system: results of a health system assessment. [PDF]

open access: yesGlob Health Action
Polack S   +9 more
europepmc   +1 more source

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