Results 191 to 200 of about 39,234,544 (355)
Privatization of health sector in ex socialist states [PDF]
Privatization of health care system in ex socialist states is one of the most controversial political and legal questions. On one part there is a widening discrepancy between the costs of health care system and the capability of public finances to cover ...
Strazisar, Borut
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Embedded Research in a Learning Health System: How a Research-Operations Partnership Informed the Development, Implementation, and Scaling of VA's Whole Health System. [PDF]
Bolton R +8 more
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
D. Louis +9 more
semanticscholar +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Disability inclusion in the Brazilian health system: results of a health system assessment. [PDF]
Polack S +9 more
europepmc +1 more source

