Results 71 to 80 of about 5,668,863 (316)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

NT Aboriginal Health Key Performance Indicators - Definitions

open access: yes, 2018
The Northern Territory Aboriginal Health Key Performance Indicator Information System (NT AHKPI) provides information on and collaboration between both government and non-government health services for reporting key performance indicator (KPI) data on ...
Department of Health
core  

Antenatal Testing Education: Assessing Health Education and Health Knowledge in a High-Risk Pregnant Population

open access: yesAmerican Journal of Perinatology Reports
Objective This study aimed to assess health knowledge and patient satisfaction in patients undergoing antenatal surveillance.
Jessica Shaker   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Health Advisory Committees Fact Sheet and Terms of Reference

open access: yes, 2017
Health Advisory Committees are being established to promote and facilitate community consultation and engagement to shape the delivery of public health services in the Northern Territory.
System Performance and Innovation
core  

Active Ageing in Urban Thailand: Evaluating the Impact of Community-Based Interventions on Health and Digital Access

open access: yesIanna Journal of Interdisciplinary Studies
Background: Thailand had become a fully aged society in 2025 and is projected to become a superaged society by 2031. Without adequate preparation, the increasing demand for older adult care could place a significant economic burden on the country ...
Juntima Rerkluenrit   +3 more
doaj  

Strong health systems are learning health systems

open access: yesPLOS Global Public Health, 2022
Kabir Sheikh, Seye Abimbola
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Lithuania: health system review

open access: yes, 2013
150 p.This analysis of the Lithuanian health system reviews the developmentsin organization and governance, health financing, health care provision,health reforms and health system performance since 2000.
Janoniene, Raimonda   +6 more
core  

376 Using a large language model to create lay summaries of clinical study descriptions

open access: yesJournal of Clinical and Translational Science
Objectives/Goals: We assessed the feasibility of using a large language model (LLM) to create lay language descriptions of study protocols for recruitment, which has the potential to improve accessibility and transparency of clinical studies and enable ...
Rebecca E Kaiser   +7 more
doaj   +1 more source

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