Results 81 to 90 of about 5,668,863 (316)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Health Advisory Committees Expression of Interest

, 2017
Health Advisory Committees are being established to promote and facilitate community consultation and engagement to shape the delivery of public health services in the Northern Territory.
System Performance and Innovation
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Kazakhstan: health system review

, 2012
xx, 154 p.Since becoming independent, Kazakhstan has undertaken major efforts in reforming its post-Soviet health system. Two comprehensive reform programmes were developed in the 2000s: the National Programme for Health Care and Development 2005–2010 ...
Rechel, Bernd, Katsaga, Alexandr, European Observatory on Health Systems and Policies, Karanikolos, Marina, Kulzhanov, Maksut, World Health Organization. Regional Office for Europe   +5 more
core  

Europeanisation of health systems : a qualitative study of domestic actors in a small state [PDF]

, 2016
Background: Health systems are not considered to be significantly influenced by European Union (EU) policies given the subsidiarity principle. Yet, recent developments including the patients’ rights and cross-border directive (2011/24 EU), as well as ...
Aluttis, Christoph, Azzopardi-Muscat, Natasha, Kristine Sorensen, Azzopardi Muscat, Natasha, Brand, Helmut, Pace, Roderick, Christoph Aluttis, Helmut Brand, Roderick Pace, Brand, Helmut; id_orcid, Sorensen, Kristine, Natasha Azzopardi-Muscat   +11 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

For the Health Centre Community Report

, 2017
The NT AHKPI Clinical Reference Group has delivered this Prompt Sheet in order to assist community health services staff in applying Continuous Quality Improvement to their NT AHKPI Initial Release Report(s).
Data Management & System Reporting
core  

Selection and Validation of Health Indicators in Prognostics and Health Management System Design [PDF]

, 2013
Health Monitoring is the science of system health status evaluation. In the modern industrial world, it is getting more and more importance because it is a powerful tool to increase systems dependability.
Jean-Remi Masse, Benjamin Lamoureux, MECHBAL, Nazih, LAMOUREUX, Benjamin, MASSÉ, Jean-Rémi, Nazih Mechbal   +5 more
core   +1 more source

The interplay of maturity-onset diabetes of the young, obesity, uncontrolled hypertension, and cannabinoid hyperemesis in the progression to end-stage renal disease: a case report

Frontiers in Medicine
BackgroundMaturity-onset diabetes of the young (MODY) is a rare monogenic diabetes with significant renal risk, especially when combined with hyperglycemia, obesity, and other factors.
Neguemadji Ngardig Ngaba, Victoria Lovallo, Anna ONeil, Xegfred Lou T. Quidet, Michael Asare, Henry Nabeta, Shagun Thakur, Riddick Osei Agyemang, Rayan Alataa, Fouad Kaddour Hocine, Karla Garcia Rodriguez, Abel Akanyijuka, Dennis Ansah, Akua Amoa, Oserefuamen Okobi, Shazia Khan, Ruchita Kodakandla, Sahil Dudhat, Shrushti Tanna, Del Orbe Eduardo, Muhammad Saleem Akhter, Rabih Nasr, Kalpana Uday, Khaja Misbahuddin   +23 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source