Results 71 to 80 of about 28,445,610 (266)

New directions in European public health research:report of a workshop [PDF]

open access: yes, 2007
Public health draws from a range of academic disciplines, social, medical and statistical, and answers questions relevant to improving the health of populations.
Álvarez-Dardet, Carlos   +21 more
core   +1 more source

Evaluating the diagnostic performance of miLab™ for detection of malaria parasites using nPCR as reference standard

open access: yesMalaria Journal
Malaria remains a leading health threat in sub-Saharan Africa, causing over 600,000 deaths annually. Ghana, ranked among the top 15 in malaria burden in Africa, relies heavily on microscopy for diagnosis due to its affordability and established use ...
Ebenezer Kojo Addae   +12 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Strengthening primary health care in the COVID-19 era: a review of best practices to inform health system responses in low- and middle-income countries

open access: yes, 2021
Amid massive health system disruption induced by the coronavirus disease 2019 (COVID-19) pandemic, the need to maintain and improve essential health services is greater than ever. This situation underscores the importance of the primary health care (PHC)
World Health Organization. Regional Office for South-East Asia
core  

Strengthening capacity to apply health research evidence in policy making: experience from four countries [PDF]

open access: yes, 2016
Increasing the use of evidence in policy making means strengthening capacity on both the supply and demand sides of evidence production. However, little experience of strengthening the capacity of policy makers in low- and middle- income countries has ...
K Aulakh, B   +21 more
core   +1 more source

Adopting AI Enhances Humanitarian Operations While Demanding Critical Trade-Offs

open access: yesAvicenna Journal of Medicine
Artificial intelligence (AI) is increasingly impacting the cooperation sector, transforming how humanitarians are operating in the field. AI tools now allow for improved health diagnostics and quality services.
Caroline Grangier   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Audit of essential medicine listing and registration status of medicines on standard treatment guidelines in Kenya, Tanzania and Uganda: Case study of malaria, tuberculosis, hypertension and type 2 diabetes mellitus

open access: yesJRSM Open
Objectives To determine alignment between national and World Health Organization (WHO) treatment recommendations, medicines prioritisation in country's essential medicines list (EML), and medicines availability in National drug register.
Deborah Babatunde   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

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