Results 91 to 100 of about 5,541,202 (305)
The Physician on a Board of Directors: Bane or Benefit?
Journal of Healthcare Leadership, 2022 Malke Borow,1 Baruch Levi,1,2 Benny Avissar,1 Leah Wapner1 1Israeli Medical Association, Ramat Gan, Israel; 2Department of Health Policy and Management, Ben-Gurion University of the Negev, Beer-Sheva, IsraelCorrespondence: Baruch Levi, Division of Law ...
Borow M, Levi B, Avissar B, Wapner L
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Health technology in perspective [PDF]
Journal of Periodontal & Implant Science, 2015 The ongoing development of information and communication technology (ICT) is taking the healthcare industry to the next level. It allows an independent healthcare system by which anyone can easily obtain tne real-time measurement of individual biometrics as well as customized prescriptions without the hassle to visit health professionals in person ...
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applying gaming technology to healthcare student education [PDF]
Introduction Historical perspectives in relation to technology & health Rationale for using ‘Nintendo Wii & Balance Board’ in health education & practice The equipment and basic costings The science behind ...
Flynn, Jonathan
core
Getting the Right Mix: Developing a primary - secondary health provider IT interface in the Waikato District Health Board [PDF]
, 2007 The article presents a study on the electronic health record systems (EHR) developed by Waikato District Health Board (DHB) in New Zealand. The DHB develop EHR with the intention of integrating primary, secondary and tertiary provider information.
Gibb, Jenny L., Haar, Jarrod M.
core +1 more source
Health technology assessment for digital health technologies
, 2023 Health technology assessment (HTA) frameworks used for making public funding decisions on digital health technologies (DHTs) have not been informed by large stakeholder preference studies and rarely cover all nine domains of the widely used EUnetHTA “Core Model”.
openaire +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Self-monitoring Practices, Attitudes, and Needs of Individuals with Bipolar Disorder: Implications for the Design of Technologies to Manage Mental Health [PDF]
, 2016 Objective To understand self-monitoring strategies used independently of clinical treatment by individuals with bipolar disorder (BD), in order to recommend technology design principles to support mental health management.
Chang, Pamara +6 more
core +1 more source