Results 71 to 80 of about 22,551,970 (267)
The political rationality of American science
, 1990 Includes bibliographical references,Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1990.by Oren Grad.Ph ...
Grad, Oren
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Tic & SociétéThis article reports on discrepancies between the initial ambitions of an international research project aiming at developing connected objects to support people living with Parkinson’s disease and its implementation in France. We present the composition
Hélène GERMAIN, Natalia DEL CAMPO
doaj +1 more source
Frontiers in Pharmacology, 2015 The increasing interest for evaluating indirect consequences of health care interventions and their interaction with patients’ behavior have put the focus on health promotion interventions including nutrition and the need to measure and evaluate them ...
Iñaki eGutiérrez-Ibarluzea +1 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The effect of mechanical compression on chondrocyte gene expression [PDF]
, 1999 Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1999.Includes bibliographical references (leaves 115-122).by Paula M.
Ragan, Paula Marie
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2018 19 p.This publication presents version 1.0 of the World Health Organization’s Classification of Digital Health Interventions (DHIs), a taxonomy developed to provide a shared and standardized language for describing how digital and mobile technologies are
World Health Organization
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source