Results 91 to 100 of about 22,551,970 (267)

Physical diagnostics of cartilage degeneration [PDF]

open access: yes, 1999
Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, February 1999."January 1999."Includes bibliographical references (leaves 219-239).by Steven Treppo.Ph ...
Treppo, Steven
core  

Corrigendum: Effectiveness and usability of the system for assessment and intervention of frailty for community-dwelling pre-frail older adults: A pilot study

open access: yesFrontiers in Medicine, 2022
Ren Siang Tan   +16 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Protocol for a health technology assessment of screening for abdominal aortic aneurysm in men

open access: yes
Following a request from the National Screening Advisory Committee (NSAC), HIQA has commenced work on a health technology assessment (HTA) of screening for abdominal aortic aneurysm (AAA) in men in Ireland.
Health Information and Quality Authority (HIQA)
core  

Mutual information relevance networks : functional genomic networks built from pair-wise entropy measurements

open access: yes, 2002
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis (S.M.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology ...
Butte, Atul J.
core  

Actin dynamics in the cell cytoplasm and the role of actin associated proteins [PDF]

open access: yes, 1998
Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1998.Includes bibliographical references.by James L.
McGrath, James L. (James Lionel)
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Protocol for a health technology assessment of extending BowelScreen to those aged 50 to 54 years

open access: yes
Following a request from the National Screening Advisory Committee (NSAC), HIQA has commenced work on a health technology assessment (HTA) of extending Ireland’s national colorectal cancer screening programme, BowelScreen, to those aged 50 to 54 years ...
Health Information and Quality Authority (HIQA)
core  

Health Technology Assessment of Metabolic Surgery for the Treatment of Comorbid Type 2 Diabetes and Obesity

open access: yes, 2022
In response to a request from the Health Service Executive (HSE), the Health Information and Quality Authority (HIQA) agreed to undertake a health technology assessment (HTA) of metabolic surgery for the treatment of comorbid type 2 diabetes (T2D) and ...
Health Information and Quality Authority (HIQA)
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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