Results 61 to 70 of about 5,578,781 (262)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Rising health spending, new medical technology and the Baumol effect [PDF]
This paper estimates the Baumol effect in health spending, using a panel data set of OECD countries. Health expenditure as a share of GDP rises in most OECD countries.
Marc Pomp, Suncica Vujic
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Data analytics based positioning of health informatics programs [PDF]
, 2017 The Master of Science in Computer Information Systems (CIS) with concentration in Health Informatics (HI) at Metropolitan College (MET), Boston University (BU), is a 40-credit degree program that are delivered in three formats: face-to-face, online, and ...
Brusic, Vladimir +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Quantifying Induced Nystagmus Using a Smartphone Eye Tracking Application (EyePhone)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground There are ≈5 million annual dizziness visits to US emergency departments, of which vestibular strokes account for over 250 000. The head impulse, nystagmus, and test of skew eye examination can accurately distinguish vestibular strokes from ...
Pouya B. Bastani +8 more
doaj +1 more source
Social technology and human health [PDF]
human development ...
David E. Bloom, River Path Associates and Karen Fang
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Comparison of Nurses’ Digital Literacy Levels: A Study in Digital and Non-Digital Hospitals
Forbes Tıp DergisiObjective: The aim of this study is to compare the digital literacy levels of nurses working in digital and non-digital hospitals and to examine the effect of demographic and professional variables on their digital competence.
Mustafa ORHAN, Süleyman MERTOĞLU
doaj +1 more source
A National Dialogue on Health Information Technology and Privacy [PDF]
, 2009 Increasingly, government leaders recognize that solving the complex problems facing America today will require more than simply keeping citizens informed.
Alan P. Balutis +4 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source