Results 141 to 150 of about 17,104,065 (353)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
ENVIRONMENTAL IMPACT ASSESSMENT OF A HEALTH TECHNOLOGY: A SCOPING REVIEW
International Journal of Technology Assessment in Health Care, 2018 Introduction: The Health Technology Expert Review Panel is an advisory body to Canadian Agency for Drugs and Technologies in Health (CADTH) that develops recommendations on health technology assessments (HTAs) for nondrug health technologies using a ...
Julie Polisena +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Health technology in perspective [PDF]
Journal of Periodontal & Implant Science, 2015 The ongoing development of information and communication technology (ICT) is taking the healthcare industry to the next level. It allows an independent healthcare system by which anyone can easily obtain tne real-time measurement of individual biometrics as well as customized prescriptions without the hassle to visit health professionals in person ...
openaire +2 more sources
International Profiles of Health Care Systems [PDF]
, 2010 Compares the healthcare systems of Australia, Canada, Denmark, England, France, Germany, Italy, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United States, including spending, use of health information technology, and ...
core
Incorporating carbon into health care: adding carbon emissions to health technology assessments.
Lancet Planetary Health, 2022 S. McAlister, R. Morton, A. Barratt
semanticscholar +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Health technology assessment for digital health technologies
, 2023 Health technology assessment (HTA) frameworks used for making public funding decisions on digital health technologies (DHTs) have not been informed by large stakeholder preference studies and rarely cover all nine domains of the widely used EUnetHTA “Core Model”.
openaire +1 more source
Self-monitoring Practices, Attitudes, and Needs of Individuals with Bipolar Disorder: Implications for the Design of Technologies to Manage Mental Health [PDF]
, 2016 Objective To understand self-monitoring strategies used independently of clinical treatment by individuals with bipolar disorder (BD), in order to recommend technology design principles to support mental health management.
Chang, Pamara +6 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source