Results 181 to 190 of about 22,551,970 (267)

Role of General Practitioners in European Health Technology Assessment, EU-HTA Innovation in Oncology as an Example. [PDF]

J Mark Access Health Policy
Widmer D, Marcos Carrera H, Ruof J, Fernando GVC, Ouvrard P, Bonnamour MC, McCarthy M, Atreya S.   +7 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Editorial: Digital health applications: acceptance, benefit assessment, and costs from the perspective of patients and medical professionals

Frontiers in Health Services
Tonio Schoenfelder, Tonio Schoenfelder, Tom Schaal   +2 more
doaj   +1 more source

Comparison of machine learning models for bradykinesia assessment using digital health technology. [PDF]

Front Digit Health
Czech MD, Deng Y, Cosman J, Crouthamel M, Zhong S, Wang L, Dorsey ER, Adams JL, Shen J.   +8 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Quantitative analytical frameworks for benefit-risk assessment in health technology assessment. [PDF]

Epidemiol Serv Saude
Suzumura EA, Bortoluzzi AFR, Nonato AC, Maia FHA, Domingues SM, Ascef BO, Campolina AG, Jahn B, Siebert U, de Soárez PC.   +9 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Institutionalization of assistive health technology in India: establishment of a national centre within the IIT-AIIMS ecosystem. [PDF]

Front Rehabil Sci
Deb S, Das R, Singh R.
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Advancing foundational models in digital health technology adoption: A systematic literature review of multidisciplinary factors. [PDF]

PLOS Digit Health
Ng HY, Ramasamy S, Muthaiyah S, Anandan A, Chen ST, Munohsamy T, Thangarasu G.   +6 more
europepmc   +1 more source