Results 31 to 40 of about 5,578,781 (262)

Smart technology for healthcare: Exploring the antecedents of adoption intention of healthcare wearable technology [PDF]

, 2019
© The Author(s), 2019. Technological advancement and personalized health information has led to an increase in people using and responding to wearable technology in the last decade.
Broom, David, Chau, K.Y., Cheung, M.L., Flint, S.W., Lam, M.H.S., Lee, K.Y., Tse, G., Tso, E.K.H.   +7 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Bayesian clinical trial designs : Another option for trauma trials? [PDF]

, 2017
The UK-REBOA Trial is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (project number 14/199/09). PP was supported by the MRC Network of Hubs for Trials Methodology Research (MR/L004933/1-R/N/P/B1).
Campbell, Marion K., Jansen, Jan O., MacLennan, Graeme, Pallmann, Philip, UK-REBOA Trial Investigators   +4 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An Application of Evidence‐Based Approaches to Engage Young People in the Design of a Global Mental Health Databank

Health Expectations
Introduction Engaging youth in mental health research and intervention design has the potential to improve their relevance and effectiveness. Frameworks like Roger Hart's ladder of participation, Shier's pathways to participation and Lundy's voice and ...
Augustina Mensa‐Kwao, Lakshmi Neelakantan, Jennifer Velloza, Emily Bampton, Swetha Ranganathan, Refiloe Sibisi, Joshua Bowes, Lilliana Buonasorte, Damian Omari Juma, Manasa Veluvali, Megan Doerr, Tamsin Jane Ford, Christine Suver, Carly Marten, The MindKind Consortium, Pamela Y. Collins   +15 more
doaj   +1 more source

Computer tablet-based health technology for strengthening maternal and child tracking in Bihar

Indian Journal of Public Health, 2016
Background: UNICEF along with the State Government of Bihar launched a computer tablet-based Mother and Child Tracking System (MCTS) in 2014, to capture real-time data online and to minimize the challenges faced with the conventional MCTS. Objective: The
Preeti Negandhi, Monika Chauhan, Ankan Mukherjee Das, Jyoti Sharma, Sutapa Neogi, Ghanashyam Sethy   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Living Lab services promoting health in the community through participation

Finnish Journal of eHealth and eWelfare, 2018
In the time of urban growth, people should be at the heart of development, too often they are forgotten. However, growth poses also a great possibility.
Arto Holopainen, Pauliina Kämäräinen, Merita Kaunisto, Heli Kekäläinen, Kirsimarja Metsävainio   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source