Results 41 to 50 of about 23,885,267 (262)

Diagnostic accuracy of 18F Prostate Specific Membrane Antigen (PSMA) PET-CT radiotracers in staging and restaging of high-risk prostate cancer patients and patients with biochemical recurrence: protocol for an overview of reviews [version 1; peer review: 2 approved]

open access: yesHRB Open Research, 2023
Background: Correct staging and risk stratification is essential in ensuring prostate cancer patients are offered the most appropriate treatment. Interest has been growing in the use of radiotracers targeting prostate specific membrane antigen (PSMA ...
Susan Ahern   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Health technology assessment of the addition of spinal muscular atrophy (SMA) to the National Newborn Bloodspot Screening Programme

open access: yes, 2023
At the request of the National Screening Advisory Committee (NSAC), the Health Information and Quality Authority (HIQA) agreed to undertake a health technology assessment (HTA) of the addition of spinal muscular atrophy (SMA) to the National Newborn ...
Health Information and Quality Authority (HIQA)
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Perception of vulnerable populations of label warnings in Global Adult Tobacco Survey (GATS) - Panama

open access: yesTobacco Induced Diseases, 2018
Background Tobacco products consumption is responsible of 148.6 million DALYS and 6.4 million deaths around the World in 2015, due to a large array associated medical conditions.
Hedley Knewjen Quintana   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Health care technology and its assessment in eight countries [PDF]

open access: yes, 1995
This report is a part of a larger study on International Differences in Health Care Technology and Spending. It discusses health care technology as a policy issue, healthcare technology in Australia, Canada, France, Germany, Netherlands, Sweden, United ...
United States. Congress. Office of Technology Assessment.
core  

Comparative analysis of breast cancer care models and patient journeys across six European countries: implications for the Austrian healthcare system

open access: yesBMC Health Services Research
Introduction The increasing prevalence of breast cancer is straining hospital-centred healthcare systems worldwide, including Austria’s. This study examined breast cancer care models across six European countries to identify alternative approaches for ...
Nicole Grössmann-Waniek   +3 more
doaj   +1 more source

Improving the monitoring of chronic heart failure in Argentina: is the implantable pulmonary artery pressure with CardioMEMS Heart Failure System cost-effective?

open access: yesCost Effectiveness and Resource Allocation, 2021
Background The CardioMEMS® sensor is a wireless pulmonary artery pressure device used for monitoring symptomatic heart failure (HF). The use of CardioMEMS was associated with a reduction of hospitalizations of HF patients, but the acquisition cost could ...
Andrea Alcaraz   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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